Using the negative exponent rule you move -2^-10 to the numerator and reverse the sign of the exponent to get:
(-2^-5 * -2^10) / -1
When you multiply the same number with different powers add the exponents.
Now you have -2^-5 + 10 / -1
Simplify: -2^5 / -1
Dividing a negative by a negative becomes positive:
Now you have 2^5, which equals 32.