Question

Drug B has is to be given 10 mg/kg/day in 2 divided doses. The patient weighs 220 pounds. The pharmacy has 250 mg capsules on hand. (Round to the nearest tenth if applicable) a. How many milligrams should the patient receive per day? ________ b. How many milligrams should the patient receive per dose? ________ c. How many capsules should the patient receive per day? ________ d. How many capsules should the patient receive per dose? ________

Answer 1

a) 996.6 mg

b) 498.96 mg

c) 4

d) 2

Explanation:

Given:

Dose to be given = 10 mg/kg/day

Number of dose to be divided = 2

weight of the patient = 220 pounds

now,

1 pound = 0.453 kg

thus,

weight of the patient = 220 × 0.4536 = 99.792 kg

a) Amount of Drug patient should receive per day = dose × weight of patient

or

Amount of Drug patient should receive per day = 10 × 99.792

or

Amount of Drug patient should receive per day = 997.92 mg

b) Now, the dose is divided in to 2 per day

thus,

The amount of drug received per dose =
`\frac{\textup{Drug received per day}}{\textup{Number of dose per day}}`

or

The amount of drug received per dose =
`\frac{\textup{997.92 mg}}{\textup{2}}`

or

The amount of drug received per dose = 498.96 mg

c) weight of capsule = 250 mg

Thus,

capsules received by patient per day =
`\frac{\textup{Dose per day in mg}}{\textup{weight of capsule in mg}}`

or

capsules received by patient per day =
`\frac{\textup{997.92}}{\textup{250}}`

or

capsules received by patient per day = 3.99168 ≈ 4

d) Capsules to be received per dose =
`\frac{\textup{Amount of drug per dose in mg}}{\textup{weight of capsule in mg}}`

or

capsules received by patient per dose =
`\frac{\textup{498.86}}{\textup{250}}`

or

capsules received by patient per dose = 1.99544 ≈ 2