Question

A patient is to receive Taxol 100 mg/m2. The patient weighs 120 lbs and is 5'8" tall. What dose of Taxol in milligrams should the patient receive? Round answers to the nearest tenth and DO NOT include units

Answer 1

164.6 mg

Explanation:

Given:

Weight of the patient= 120 lbs

Height of patient = 5'8" = 5 × 12 + 8 = 68 inches

Dose of Taxol to be administered= 100 mg/ m²

Now,

the surface area of the body of patient =
`\textup{(Weight in kg)}^(0.425)*\textup{(Height in cms)}^(0.725)*0.007184`

Also,

weight of patient in kg = 120 × 0.454 = 54.48 kg

Height of patient in cm = 68" × 2.54 = 172.72 cm

therefore,

Body surface area =
`\textup{(54.48)}^(0.425)*\textup{(172.72)}^(0.725)*0.007184`

or

= 5.47 × 41.89 × 0.007184

or

= 1.646 m²

Hence,

Dose of Taxol to be received by the patient

= 100 mg/m² × surface area of the patient

= 100 × 1.646

= 164.6 mg