Question

Which of the following descriptions about RNA is not correct?

a. Double-stranded regions of RNA typically take on an B-form right-handed helix.
b. RNA is hydrolyzed rapidly under alkaline conditions due to its extra hydroxyl group compared to DNA.
c. Double-stranded regions of RNA can form between two self-complementary regions of the same single strand of RNA.
d. G-U base-pairing is typically allowed in complementary RNA-RNA pairing.
e. tRNA contains minor bases such as inosine, pseudouridine, or 7-methylglucanosine.

Answer 1

The correct answer is option a. "Double-stranded regions of RNA typically take on an B-form right-handed helix".

Step-by-step explanation:

Most of the native double-stranded DNA is on an B-form right-handed helix, following the structure proposed by Watson and Crick with about 10–10.5 base pairs per turn. However, double-stranded RNA does not follow this structure, and most regions have an A-form structure. The A-form right-handed helix have slightly more base pairs per turn, which makes it 20-25% shorter than B-DNA.