Answer:
The correct answers are e. "all of the above statement regarding smallpox are correct".
Step-by-step explanation:
Smallpox vaccination is one of the most clear examples of the benefits of performing a global vaccination program, because smallpox has been officially eradicated worldwide in 1980. However, some precautions regarding this disease should be taken, as is a very pathogenic diseases that is spread through respiratory droplets. The smallpox vaccine contains live vaccinia virus and it may revert to pathogenicity, therefore its application should be performed by an expert to assure that the virus does not affect the patient.