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Twogenes,

A and B, are located 10 maps units fromeach
other. A third
gene,
C, is located 15 map units from B and 5 mapunits
from A. A parental
generation
consists of AAbbCC and aaBBccindividuals. The F1
are then test-
crossed to
aabbcc individuals. What percentage ofthe offspring would
you
expect to be
AaBbCc?

1 Answer

4 votes

Answer:

5%

Step-by-step explanation:

We have the following loci map:

C/c -------------A/a--------------------------B/b

5 m.u. 10 m.u.

The parental cross was between the individuals:

  • CCbbAA, which can be written as CAb/CAb.
  • ccBBaa, which can be written as caB/caB.

Each parental individual can produce only 1 type of gamete, so the F1 will be homogeneous with the genotype: CAb/caB.

The F1 are test crossed to cba/cba individuals.

CAb/caB X cab/cab

The homozygous recessive can only produce cba gametes.

The F1 can produce 8 types of gametes:

  • The parentals: CAb and caB
  • The crossovers between the genes C/c and A/a: CaB and cAb
  • The crossovers between the genes A/a and B/b : CAB and cab
  • The double crossovers: Cab and cAB

The question is asking about the percentage of offspring that will have the genotype CAB/cab

The cab chromosome comes from the homozygous recessive individual with a probability of 1.

The CAB chromosome comes from the F1 individual, and was a result of crossing over between the genes A/a and B/b.

The formula to relate genetic distance with recombination frequency is:

Genetic Distance (m.u.)= Recombination Frequency X 100.

In our problem, Genetic distance between A/a and B/b loci is 10 map units.

Therefore:

10 m.u. = (Recombination Frequency between A/a and B/b) x 100.

0.1 = Recombination Frequency between A/a and B/b

When crossing over happens between the A/a and B/b genes, both CAB and cab are generated, so each of them will appear in a frequency of half the total recombination frequency between those genes, to add a total of 0.1.

The gamete CAB will appear with a frequency of 0.05.

The gamete cab will appear with a frequency of 1.

The percentage of the offspring that will be CAB/cab is:

0.05 x 1 x 100% = 5%

User Martinos
by
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