Answer:
The correct answer is option B. B cells.
Explanation:
An antibody-mediated immune response is an immune response that involves the B cells to recognize the antigen or pathogen present in the blood or the lymph of an individual that is the reason it is also known as the humoral immune response.
The primary response in the antibody-mediated response is B cells as they are activated by the chemicals released by the helper T cells and start producing plasma B cells and memory B cells.
Thus, the correct answer is option - b. B cells.