Question

Citrate produced in the mitochondria is exported to the cytosol by the citrate transporter. In the cytosol, citrate is converted to ____1_____. What enzyme is activated by increased levels of citrate? ____2_____?

a. (1) malate and acetyl-CoA; (2) fatty acid synthase
b. (1) acetyl-CoA and oxaloacetate; (2) fatty acid synthase
c. (1) malonyl-CoA; (2) acetyl-CoA carboxylase
d. (1) acetyl-CoA and oxaloacetate; (2) acetyl-CoA carboxylase

Answer 1

d. (1) acetyl-CoA and oxaloacetate; (2) acetyl-CoA carboxylase

Step-by-step explanation:

ATP- Citrate lyase (ACLY) is an enzyme present in the cytosol. ATP- Citrate lyase (ACLY) is involved in breaking down the citrate, once it has arrived in the cytosol, into acetyl-CoA and oxaloacetate.

Acetyl-CoA carboxylase is produced as a result of increased levels of citrate in the cytosol. This enzyme plays an important role in the regulation of the synthesis of fatty acids as well as degradation of the fatty acids.