For this case we have that by definition, a monomial is an algebraic expression that consists of a single term or in which the terms that form it are related by the product operation.
Example:
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On the other hand, the GCF is the largest common factor that divides numbers without leaving any residue.
Option A:

The GCF is 3:

Option B:

The GCF is 2:

Option C:

The GCF is 2x:

Option D:

This expression cannot be obtained a GCF
Answer:
OPTION D