Answer:
Quadrant #2 is the correct one.
Explanation:
Reason being that if you had a dot in quadrant 4, rotating it 180 degrees clockwise or counter-clockwise will leave you at the same spot in the quadrant of its opposite. For example: a point in quadrant 1 rotated 180 will be in quadrant 3. Point in quadrant 2 will be in quadrant 4.