Answer: 729 and 2,187
Step-by-step explanation: When we are looking at this pattern, we can see that the numbers are changing each time. In this sequence, we are multiplying our numbers by 3 so we would find our next two numbers by multiplying 243 by 3 and the product of 243 and 3 by 3.
243 x 3 = 729
729 x 3 = 2,187
Therefore, the next two numbers in the sequence would be 729 and 2,187.