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When the human virus, HIV, first appeared, the mortality rate was close to 100%. However, recent information shows some individuals are unaffected by the virus. Why is this not surprising?

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Answer:

Because of Mutation

Step-by-step explanation:

Every individual has a different genetic makeup. Most of the individuals have traits that protect them from certain diseases. The resistance to HIV is seen in approximately 1% of the individuals. The resistance is the result of changes in the factors that contribute to the attachment of HIV to the cell.

An HIV virus needs a chemokine co-receptor CC5, for the entry in the cell. In some individuals, a mutation of CC5 is present and is known as CCR5-Δ32 . This mutation doesn't allow the virus to enter the cell because it cannot attach itself to this receptor.

So, some individuals are not affected by HIV because of the mutation.

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