Question

The setting of “the most dangerous game” is that a strong or weak topic

Answer 1

It's a weak topic

Step-by-step explanation:

It's true that setting has a strong impact on a literary piece, both place and time setting. So, if you want to analyse a literary text by its setting, you can just say: "The fate of a Fallen Woman in Victorian England."

'Victorian England' is already a setting, the reader knows you are writing about a fallen woman e.g Tess (of the d'Urbervilles) in the 18th century.

I would have used the work you cited as an example, but I have not read it and I don't want to mislead you.