Answer:
uncontrolled excessive growth of cells in the tissue
Step-by-step explanation:
Contact inhibition is a cellular mechanism where cell growth is arrested when adjacent cells are in contact with each other. Contact inhibition serves to arrest further cell growth beyond a monolayer, by limiting the migration and/or proliferation of cells in a tissue or organ. In consequence, contact inhibition is critical for normal cells to stop proliferating. When contact inhibition is disrupted, cells undergo uncontrolled growth, which leads to the development of cancer and tumor progression.