Answer:
This is the proper order as they are produced in the ovary.
Primary Follicle ,Secondary follicle, Graffian follicle, Corpus luteum and Corpus albicans
Step-by-step explanation:
- Primary Follicle: During the first 5 months of developement, a finite no.of primary follicles form in the fetal ovary. They consists of oocytes surrounded by a single layer of squamous follicular cells. These follicles were remain in the process of first meiotic division. At puberty they begin to develop further and become primary follicles.
- Early primary follicle: At the start of each menstrual cycle a limited number of primary follicles begin to develop. The first stage is the early primary follicle which consists of central oocyte surrounded by a single layer of cuboidal follicular cells.The zona pellucida is a thin band of glycoproteins that seperates the oocytes and follicular cells.Proteins on the surface of sperm will bind to specific glycoproteins in the zona pellucida.
- Late Primary Follicle: This stage reached when the follicular cells proliferate into a stratified epithelium known as the zona granulosa. The zona pellucida becomes enlarged.
- Secondary Follicle: There is the appearance of antrum within the granulosa layer.The antrum contains fluid which is rich in hyalurone and proteoglycans.The increase in the cell layers of the zone granulosa, the thicker zona pellucida and larger oocyte. At this stage,a layer of cells outside the follicle becomes evident. These cells compose theca externa and production of estrogens.
- Graafian follicle: It is the stage after the first meiotic division has completed but before the ovulation.The oocyte is now a 2N haploid.The follicle is characterised by a large follicular antrum.Th secondary oocyte is surrounded by the zona pellucida and a layer of several cells known as corona radiata.
- Corpus Luteum: After the release of the ovum the remaining cells of the granulosa and the theca interna form the corpus luteum. The center contains the remains of the blood clot that formed after the ovulation.Surrounding the clot are granulosa lutein cells on the outside theca luein cells.These cells produce progesterone and to lesser extent cholestrol. The granulosa lutein cells comprises of steroid producing cells with pale cytoplasm indicating the presence of lipid droplets.Theca lutein cells are smaller and more deeply stained. Blood vessels penetrate into the region of granulosa lutein cells allowing them to take up the cholestrol and synthesize the progesterone.The activity of the cells of the corpus luteum is sustained by luteinizing hormones. If the ovum is fertilized and implants in the uterine wall HCG replaces leutinizing hormone to sustain the activity of the cells in the corpus luteum.
- Corpus Albicans: If fertilization does not occur the cells of corpus luteum remain active for roughly 14 days until the levels of LH falls and corpus luteum involutes to form corpus albicans. The secretory cells of corpus luteum degenerate are phagocytosed by macrophages and replaced by fibrous material.