Question

Which of the following molecules cannot cross the mitochondrial membrane (due to a lack of a transporter)? a. Acetyl CoA

b. Citrate
c. Malate
d. Pyruvate

Answer 1

a. Acetyl CoA

Step-by-step explanation:

Acetyl-CoA is produced in the mitochondria by the process of oxidative decarboxylation of pyruvate and β-oxidation of the fatty acids.

However, both acetyl CoA and Oxaloacetate cannot cross mitochondrial membrane. But the two join together to form citrate and thus, citrate can cross the mitochondrial membrane.