Question

Which of the following is a change in the sequence that leads to formation of a stop codon?

missense mutation
nonsense mutation
silent mutation
deletion mutation

Answer 1

-nonsense mutation

Step-by-step explanation:

Non-sense mutations can be described as mutations that to formation of a non-sense or stop codon in mRNA made from mutated gene. There are a total of 64 codons, out of which 61 code for specific amino acids and 3 codons act as stop codon or non-sense codons.

As these codons provide signal for termination of transcription, non-sense mutations lead to formation of a incomplete or truncated proteins due to premature termination of translation.

Thus, the correct answer is 'second option.'