70.5k views
5 votes
How does CRA-cAMP positively regulate the lac operon?

User Nicolas D
by
8.0k points

1 Answer

5 votes

Answer:

The CRA-cAMP complex increases the rate of expression of lac operon when glucose is absent and lactose is present as nutrient.

Step-by-step explanation:

CRP is the catabolite gene activator protein that forms a complex with cAMP. The CRP-cAMP complex facilitates the binding of RNA polymerase to the promoter region of the lac operon. This robust binding as stimulated by CRP-cAMP complex is followed by the formation of open complex and initiation of gene expression.

Hence, the CRP-cAMP complex positively regulates the lac operon and increases its expression when glucose is not present.

User Pooya Yazdani
by
8.0k points
Welcome to QAmmunity.org, where you can ask questions and receive answers from other members of our community.