Answer: First option.
Explanation:
To find which line contains the point (2,1), we can substitute the coordinates into each equation of the line provided in the options:
First option:

It contains the point (2,1)
Second option:

It does not contain the point (2,1)
Third option:
It does not contain the point (2,1)
Fourth option:

It does not contain the point (2,1)