Answer:
-2B
(I guess this is what you are looking for; didn't need A or C).
Explanation:
It seems like to wants us to to find
in terms of
.
First thing I'm going to do is rewrite
using the quotient rule.
The quotient rule says:

So that means for our expression we have:

Second thing I'm going to do is say that
.


Now I know 16 is 4 squared so the third thing I'm going to do is replace 16 with 4^2 with aim to use power rule.



The fourth thing I'm going to is apply the power rule. The power rule say
. So I'm applying that now:



So we are given that
is
. So this is the last thing I'm going to do is apply that substitution:



