Answer: Last option.
Explanation:
The equation of a circle in Center-radius form is:

Where the center is at the point (h,k) and "r" is the radius.
If the center of this circle is at the origin, means that:

Since the radius is 4, then:

Now we need to substitute these values into the equation of the circle.

Simplifying the equation, we get:

This matches with the last option.