Answer:
Prophase is the first phase of M-phase of cell division which is marked by many changes taking place in the dividing cell which are:
1. Chromatin condenses and becomes more coiled.
2. Chromosomes are seen as a pair of sister chromatids with a centromere.
3. Nucleolus-site of rRNA synthesis disappears.
4. Mitotic spindle- formation begins between two pairs of centrioles.
5. Nuclear envelope- disappears at late prophase.