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. The bleeders disease, hemophilia, is X-linked recessive. If a normal male and a female who is a carrier of the hemophilia allele decide to have children, what are the chances any of the offspring will have hemophilia? Can male offspring be carriers of the trait?

User Zaphoid
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2 Answers

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XAY * XAXa

None of the females will have hemophilia
50% of the males will have hemophilia

Males cannot be carriers of X linked traits because they only have one X chromosome so they express everything that is on that chromosome.
User Peter McKenzie
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Answer:

The chance that any of the offspring having hemophilia is 25% or 0.25. No male will be a carrier.

Step-by-step explanation:

Normal Male = X Y

Carrier Female = Xh X

Thus, the genotype of their possible offsprings will be X Xh, X X, Xh Y, X Y.

2 normal children, 1 female carrier and 1 infected male.

The chance of any offspring having hemophilia is 1/4 as only the Xh Y offspring will have hemophilia, the other X Xh will be a carrier and not have hemophilia.

A male cant be a carrier of an X linked trait like hemophilia but will be an infected or not. A male offspring could be infected with a probability of 0.5.

User Manesh Timilsina
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