Answer:
The Mississippi River is one of the most important rivers in the United States, being the longest in the nation and, together with the Missouri River, forming one of the main river basins of the entire continent.
Due to its location close to the geographic center of the country, historically it was configured as one of the main commercial routes for the production of different raw materials, from all over the country.
In addition, the Mississippi River marked for many years the western limit of the United States, after which were the native territories, which were gradually being incorporated into the United States through westward expansion.