Answer:
C) Without question, our relationship is in trouble, and we need help.
Step-by-step explanation:
The conjunctive adverbs however and in spite of demonstrate contrast between ideas. Another conjunctive adverb (still) signifies concession. Yet the underlined sentence "our relationship is in trouble, and we need help" is not related to the preceding sentences of the paragraph by way of contrast or concession to their ideas.
The phrase without question adds logical emphasis and confirms the obvious fact that the relationship is in trouble. C would be the correct choice.