Answer:
no, it cannot
Explanation:
a difference of square is: a² - b² = (a - b)(a + b)
looking at the expression (5z+3)(-5z-3), we see that it does not fit the criteria of the breakdown of a perfect square, as (-5z-3) has a negative a term (-5z)
if we FOILed (5z+3)(-5z-3) out, we would get:
-25z² - 30z - 9, which is not a difference of squares