Answer: The correct options are statement first and fourth that is -
It is synthesized toward the replication fork and it is synthesized in the 5′ to 3′ direction
Explanation: Leading strand in DNA is the strand of new DNA being synthesized in the same direction where the replication fork is moving. The movement of replication fork allows the access of template for the new DNA.
The DNA synthesis is continuous in the leading strand. It is synthesized in the 5' to 3' as DNA synthesis always takes place in this direction. This is because dNTP ( deoxyribonucleoside triphosphate) provides free 3' OH group where new dNTP can be added by the enzyme DNA polymerase.