Answer: A. ambition devoid of morality destroys everything in its path.
Explanation: The statement that best describes the main theme in Macbeth is ambition devoid of morality destroys everything in its path. In Act I of "The Tragedy of Macbeth" by William Shakespeare, we are presented with a triumphant warrior who receives the king's favors. After the witches' prophecies nor he nor Lady Macbeth can stop the uncontrollable ambition that drives them to commit several murders.