Answer:
Disadvantage of franchising that is best demonstrated by isaac's situations is DAMAGED REPUTATION
Step-by-step explanation:
Because Isaac who is a franchise owner of a fast food restaurant reputation was damaged when another franchisee was accused of using artificial meat in its hamburgers which is why sales at isaac's franchise location drop dramatically.
A person reputation can be damaged by telling lies about them or through accusation which can eventually damaged such person reputation in the society.