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The 5′cap on an mRNA is important for which of the processes listed below?

ribosomal interaction
initiation of translation
intron splicing efficiency
initiation of transcription
primer removal
transcription of the mRNA molecule
stability of the mRNA molecule

1 Answer

7 votes

The correct answers are:

• initiation of translation

During the initiation of translation the small subunit of the ribosome binds to the 5' end of mRNA with the help of initiation factors.

• stability of the mRNA molecule

5’ cap prevents the degradation of mRNA by exonucleases.

• intron splicing efficiency

5’ cap is involved in promotion of 5′ proximal intron excision.

Another function of 5’ cap is the regulation of nuclear export (transport of mRNA from nucleus to cytoplasm).

User Guillaume Thomas
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