The correct answer is a) Dr. Wong could publish his data in a scientific journal and have different investigators try to reproduce his results. This is due to external validity, when data from a research can be confirm and reproduced, after selecting a proper sample size and determine alfa and beta power, for the study. If no bias exists, other researchers should be able to replicate and validate Dr’s Wong Results.
B and C options are both unacceptable due to ethical issues, and D is incorrect based on the central limit theorem; if Dr’s Wong sample is at least 30 in number (for each group: A=test group and B=control group) the statistical inferences can be translated into larger populations. Smaller samples than this, are not recommended due to bias and internal validity.