Innate: keratinized epithelium
stratified squamous epithelium hypodermal areolar connective tissue antigen presenting cells major histocompatibility complexes complement (antibody -dependent pathway )
Innate or non-specific response is the first defense against invaders. Components of this response include physical (e.g. skin . mucosa) and chemical barriers against pathogens and cells such as Natural Killer cells, macrophages, neutrophils, dendritic cells, mast cells, basophils, eosinophils. Innate response reacts immediately.
Adaptive: immunoglobulin plasma cells agglutinin
helper t cells memory t cells cytotoxic t cells cd4+cells
t lymphocytes
Adaptive immune response or specific response is specific to the pathogen presented and mediated by lymphocytes, B and T cells. Adaptive immune response creates immunological memory after the first, initial l response to a specific pathogen which leads to enhanced response.