The right answer is Drug tolerance.
The tolerance of a drug can be considered as the ability of the body to support a certain dose of a drug.
Drug tolerance, on the other hand, refers to the decrease of the reaction at repeated constant doses of a drug or the need to increase the doses to maintain a constant effect. Tolerance to the drug may result in physical (physiological) or emotional dependence, which is a state of adjustment associated with withdrawal syndrome upon discontinuation of repeated drug exposure.