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This classification of drug typically changes the brain's chemistry and reduces its ability to create its own endorphins.

User BrandonAGr
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Answer:

depressants

Step-by-step explanation:

User David Peters
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Depressant drugs typically distort the brain’s chemistry and reduce its ability to create its own endorphins. Depressants also slow down the activity of the central nervous system.
User Kaweesha
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