Answer:
Correct answer is The Eastern Roman Empire became wealthy and powerful.
Step-by-step explanation:
First option is not correct as the country was unified at the time and this event didn't change situation that much.
Second option is also not correct as customs of the Empire were already spread across the whole country.
Third option is correct as Constantinople had a great position that allowed trade and many other labors to develop, thus strengthening the Empire.
Last option is not correct as this connections were not affected much, as we have said.