Question

The key aspect of receptor-gating in the associative induction of hippocampal LTP is that Group of answer choices the NMDA receptor acts as a molecular coincidence detector. both the NMDA and AMPA channels must be open in order for the cell to depolarize. The NMDA receptor allows the flow of magnesium into the cell. all glutamate receptors open automatically whenever glutamate is in the synaptic cleft. the AMPA receptor allows calcium into the cell only after the NMDA receptor is activated.

Answer 1

The correct answer is NMDA receptor acts as a molecular coincidence detector.

Step-by-step explanation:

The hippocampus works entirely for memory processes (especially new learning). Lasting depression (LTD) is also considered as another form of expression of synaptic plasticity. Long-term potential occurs when pyramidal neurons are depolarized and stimulated by excitatory input. The neurophysiological basis for LTP is certainly related to a subtype of NMDA of the glutamate receptor. This receptor behaves as a coincidence detector between pre- and post-synaptic activity, with an increase in glutamate release at the presynaptic level coinciding with a Postsynaptic depolarization that allows the entry of ca2 +. The NMDA receptor has been proposed as the basic mechanism of learning, because it has the ability to associate different signals, for all this it is necessary to know what neurotransmitters are, their function and what is the role of the receivers in them.