Question

Charcot-Marie-Tooth is a muscular wasting disease that affects 1 in 2,500 people. Researchers have discovered that this occurs when a large gene on the short arm (p-arm) of chromosome number 17 makes a new copy of itself. What kind of chromosomal mutation is this?

Answer 1

Charcot-Marie-Tooth disease involves a duplication mutation on the short arm of chromosome 17, causing the gene to make an extra copy of itself.

Step-by-step explanation:

The type of chromosomal mutation described for Charcot-Marie-Tooth disease, where a large gene on the short arm (p-arm) of chromosome number 17 makes a new copy of itself, is known as duplication. This type of mutation occurs when a segment of a chromosome is copied and inserted back into the genome, leading to extra copies of genetic material. Such duplications can disrupt the normal function of genes and lead to genetic disorders.