Answer:
slowed the spread of technology and innovation
hurt farmers and merchants who depended on trade
Step-by-step explanation:
When the Ming dysnastia decided to isolate China, it aimed to promote domestic reforms, to preserve cultures and racial purity and to prevent European influence in the region. However, although a large part of these objectives were achieved, isolation also caused problems in the country. The main problem was the disadvantage that farmers and traders who sold their products, often to European nations, lost this possibility and had their economic conditions unfavorable. A second problem was that China was prevented from having access to possible technologies that other nations could develop.