Answer:
5. Generation III
6. Yes
7. No
8. 8 and 9
Step-by-step explanation:
5. Males are depicted by square symbols. The most squares are found in generation III (4 males) so this is the answer.
6. Carriers are heterozygotes, which means they have one copy of the sickle cell allele. Let's imagine the normal allele is A and the sickle cell allele is a. A cross between two carriers is Aa x Aa. Here are the possible genotypes:
A a
A AA Aa
a Aa aa
Individuals with an aa genotype have sickle cell disease. So 1:4 children of two carriers will have the disease.
7. Normal h0m0zygous individuals have the genotype AA. It is not possible for them to have an affected child, because the child will always inherit one of the A alleles from that individual (it does not matter whether they inherit A or a from the other parent, their genotype can only be Aa or AA, which are both unaffected.
8. We are looking for two affected individuals in the same family. We will be able to see they are affected because their symbols will be shaded. Individuals 8 and 9 are both heterozygous (carriers) and have 4 children. 2 affected and 2 unaffected.