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What is necessary for a ligand-gated channel to open its gate?

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asked Aug 18, 2021 3.5k views

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What is necessary for a ligand-gated channel to open its gate?

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Hoffm asked

by Hoffm

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Ligand-gated ion channels open when a chemical ligand such as a neurotransmitter binds to the protein.

Dominic Mitchell answered Aug 23, 2021

by Dominic Mitchell

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For ligand-gated channels, ligands always bind to the N-terminal extracellular side of the membrane protein for there to be a conformational change, opening the gate, and permiting the flow of ions in

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What is necessary for a ligand-gated channel to open its gate?

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