Answer:
The city of Buffalo, located on the shores of Lake Erie and the Niagara River, is located in the western region of New York State, a few kilometers from the border with Canada.
If you leave this city heading east about 240 kilometers you will reach the city of Syracuse, also located in the State of New York.
Now, if from Syracuse you decide to travel another 45 miles south, you will arrive to Marathon, New York, a small town located on the banks of the Tioughnioga River.