Question

Prader-Willi syndrome is a genetic disorder involving a partial deletion of chromosome 15q on the paternal chromosome. When both copies of a gene (or chromosome) are functional but only one is expressed, this is an example of ________.a) position effect variegationb) chromatin modificationsc) histone acetylationd) genomic imprintinge) X-inactivation

Answer 1

The correct answer is d) genomic imprinting.

Step-by-step explanation:

Genomic imprinting is a biological process by which specific modifications in the germ line that produce differences in the expression of the genetic material that is biochemically marked indicating its parental origin. The Prader-Willi syndrome is one of the best known and most studied examples in relation to pathologies produced by genomic imprinting. Prader-Willi syndrome is a complex genetic disease that is fundamentally neurological. Its appearance is due to a deletion of a fragment of chromosome 15 derived from the father.