Final answer:
OPTION A
The combination of large charges close together will result in the largest attraction between particles because of the higher product of charges and smaller separation distance.
Step-by-step explanation:
To determine which combination would result in the largest attraction between particles, we must understand that the electrostatic force is dependent on two major factors: the magnitude of the charges and the distance between them. The force of attraction is directly proportional to the product of the charges and inversely proportional to the square of the distance between them, according to Coulomb's law. Therefore, large charges close together will experience the strongest attractive force due to the higher product of charges and smaller separation distance, leading to a larger value for the electrostatic force.