Question

Define tumor-suppressor genes. Why is a mutation in a single copy of a tumor-suppressor gene expected to behave as a recessive gene

Answer 1

The correct answer is :

If the mutated gene was dominant, it would be impossible to be transported to the offspring, since the organism that carries this gene would not survive because of cancer.

It involves loss of function mutation

Step-by-step explanation:

Tumor suppressor genes are the genes that regulate the cell cycle, cell or DNA repair, tells the cell when to die or apoptosis prevents the cell from oncogenes by suppressing them. They also control their own function.

Mutations in these genes are generally express themselves as recessive genes which means they can only express if both copies of the mutated gene present together or no loss of control if one copy present.

If it would be dominant there would be no chance of mutation to pass to the next generation of the cell and an individual with cancer would not survive.