Answer:
4-The 2 strands of DNA separate
2-mRNA is built based on the DNA template
3-mRNA leaves the nucleus
1-mRNA connects with a ribosome
8-tRNA brings an amino acid into the P site
7-tRNA brings an amino acid into the A site
9-tRNA leaves the P site and a peptide bond is formed between the amino acids
6-The mRNA + attached tRNA shifts, moving the tRNA from the A site to the P site
5-The entire mRNA strand is translated into amino acids and a polypeptide is formed
Step-by-step explanation:
In protein synthesis, the first step is to synthesize messenger RNA, mRNA. The coping process of the DNA section for the desired protein is called transcription, and it happens in the nucleus. In the nucleus, there exists the preRNA which is the precursor of the mature mRNA. These molecules possess long intermediate sequences called introns that do not codify for proteins. It occurs a posttranscriptional modification that eliminates introns and makes the RNA mature as mRNA. snRNA means "small nuclear RNA". These are small RNA molecules located in the nucleus and are implicated in the RNA maturation process. They associate with proteins composing the small nuclear ribonucleoproteins, and their function is to contribute to the initial mARN processing that transcribes from DNA and that must maturate to be exported from the nucleus. mRNA means "messenger RNA". These molecules are carriers of the genetic information and are in charge of transporting it from the genome to the ribosomes. They are the mold for the new protein synthesis. Their nucleotide sequence is complementary with the nucleotide sequence of a particular DNA segment.
After transcription, it occurs translation, when the formed mRNA moves to the cytoplasm through the nucleus membrane pores. Protein synthesis is initiated in the cytoplasm when mRNA meets a free ribosome, the primary structure for protein synthesis. Ribosomes are composed of the association of proteins with rRNA and tRNA and can be found in the rough endoplasmic reticulum or floating in the cytosol. rRNA means "ribosomal RNA". They are the principal ribosomal component. Ribosomes are constituted by two subunits. One of them is a big RNA molecule associated with about 20 proteins. The other subunit is composed of three RNA molecules associated with about 50 proteins. tRNA means "transference RNA". These molecules are in charge of transferring activated amino acids from the cytosol to the ribosomes where the new protein is being synthesized. During translation, the ribosome recognizes the initiation codon of the mRNAs, which is read in the 5´ to 3´ direction. In the ribosome, there are two free sites available for the tRNA arrival, the P site and the A site. One tRNA reaches first the P site and then another tRNA reaches the A site, and transfer the correct amino acids to build the polypeptide chain. Each amino acid is specified by a codon formed by three bases in the mRNA. When both sites are occupied, the tRNA located in the P site leaves the ribosome, so the other tRNA moves to the P site and let available the A site, which will be occupied by a new tRNA.
mARNs have a start and end codon that tells the ribosome where to start and stop adding amino acids. When the ribosome reaches the end codon, a protein factor joints the codon and forbids that a new tRNA get to the free A site. At this point the protein synthesis is finished. The protein is then synthesized from the amino terminus to the carboxy terminus.