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If the fatty acid palmitate (16:0) radiolabeled with 14C in C-16 were metabolized by mammalian cells under anaerobic conditions, what compounds would be tagged with 14C and in what position

User Hari Das
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1 Answer

3 votes

The options are missing from the question,

Below are the options.

A) Tag would be CO2

B) Acetate in C-2

C) 1 uvate in C-3

D) pyruvate in C-3

E) oxaloacetate on C-1

F) palmitate in C-16

The correct answer to the question is option B

ACETATE IN C-2

If palmitate (16:0) which is a fatty acid radiolabeled with 14C in C-16, when metabolized under anaerobic conditions by mammalian cells,the compound that will be tagged with 14C will be ACETATE and the position it will be will be C-2

In an anaerobic condition, anaerobic CoA which is formed after the oxidation of fatty acid will now move into the Kreb cycle as a result of oxygen deficiency, taking the form of acetate,it will enter cytosol and will further be used for other purposes.

User Daniel Tovesson
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