You can start by determining all common factors between the like terms (27 with 18; u with u; v with v).
Now, do 27 and 18 have common factors? Yes --> that would be the 9
You can simplify that term to

Do
and
have common factors? Yes -->

You can simplify that term to

Do
and
have common factors? Yes -->

You can simplify that term to

As the final step, you can times all those final terms together to reach your answer as -

Hope this helped a lot :)