Answer:
The continuous spread of Europeans, conflicts on keeping territory/land, differences in cultures
Step-by-step explanation:
When the Europeans came they brought diseases and other things with them that helped and hurt the Indian tribes. The American Europeans wanted to spread out more and continue west, this is where the tribes were located and the Indians wanted to keep their sacred lands for religious, living, etc. purposes. While the Europeans wanted lands for different purposes. The Europeans farmed, practiced Christianity, and only spoke English. All these things led up to the Battle of Horseshoe Bend.