Final answer:
The two lines in the excerpt that indicate the subject are about finding significance in small things.
Step-by-step explanation:
The two lines in this excerpt from the poem "A Grain of Sand" by Frances Ellen Watkins Harper that indicate its subject are:
A. Do you see this grain of sand
Lying loosely in my hand? Do you know to me it brought
B. Just a simple loving thought?
These lines highlight the subject of the poem, which is the significance and meaning that can be found in even the smallest and simplest things.