Question

Which condition is autosomal recessive?

a) neurofibromatosis type 1
b) hemophilia
c) sickle cell anemia
d) Rett syndrome

Answer 1

c, sickle cell anemia

Step-by-step explanation:

When you are conceived you (generally) receive one set of chromosomes from your mom and one from your dad. Recessive diseases mean that you must receive 2 copies of the mutated gene (disease gene) to express the disease (one from mom and one from dad). Dominant means that you only need one copy of the mutated gene to express the disease.

Sickle cell anemia is a disease caused by a mutation in the hemoglobin-Beta gene found on chromosome 11. The mutation is on an autosome (not a sex chromosome). You need two copies of the bad gene in order to express it.